PDB entry 2ihw

View 2ihw on RCSB PDB site
Description: Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form
Class: transferase
Keywords: cubic core, homo trimer, apo form, TRANSFERASE
Deposited on 2006-09-27, released 2006-12-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.186
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwa_
  • Chain 'B':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwb_
  • Chain 'C':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwc_
  • Chain 'D':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwd_
  • Chain 'E':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwe_
  • Chain 'F':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwf_
  • Chain 'G':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwg_
  • Chain 'H':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ihwh_
  • Heterogens: ACT, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ihwA (A:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwA (A:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ihwB (B:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwB (B:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ihwC (C:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwC (C:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ihwD (D:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwD (D:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ihwE (E:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwE (E:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ihwF (F:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwF (F:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2ihwG (G:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwG (G:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2ihwH (H:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ihwH (H:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk