PDB entry 2ih5

View 2ih5 on RCSB PDB site
Description: Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target base partner position
Class: transferase/DNA
Keywords: DNA, DNA methyltransferase, target base partner, abasic site analog, base flipping, nucleotide flipping, TRANSFERASE-DNA COMPLEX
Deposited on 2006-09-25, released 2007-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: modification methylase taqi
    Species: Thermus aquaticus [TaxId:271]
    Gene: taqIM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ih5a1, d2ih5a2
  • Chain 'B':
    Compound: 5'-d(*gp*tp*tp*cp*gp*ap*tp*gp*tp*c)-3'
    Species: synthetic, synthetic
  • Chain 'C':
    Compound: 5'-d(*gp*ap*cp*ap*(3dr)p*cp*gp*(6ma)p*ap*c)-3'
    Species: synthetic, synthetic
  • Heterogens: NEA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ih5A (A:)
mglppllslpsnsaprslgrvetppevvdfmvslaeaprggrvlepacahgpflrafrea
hgtayrfvgveidpkaldlppwaegiladfllwepgeafdlilgnppygivgeaskypih
vfkavkdlykkafstwkgkynlygaflekavrllkpggvlvfvvpatwlvledfallref
laregktsvyylgevfpqkkvsavvirfqksgkglslwdtqesesgftpilwaeyphweg
eiirfeteetrkleisgmplgdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkp
gwvdyeknhsglwmpkerakelrdfyatphlvvahtkgtrvvaawderaypwreefhllp
kegvrldpsslvqwlnseamqkhvrtlyrdfvphltlrmlerlpvrreygfhtspesarn
f

    Sequence, based on observed residues (ATOM records): (download) 
    >2ih5A (A:)
vetppevvdfmvslaeaprggrvlepacahgpflrafreahgtayrfvgveidpkaldlp
pwaegiladfllwepgeafdlilgnppygivgeaskypihvfkavkdlykkafstwkgky
nlygaflekavrllkpggvlvfvvpatwlvledfallreflaregktsvyylgevfpqkk
vsavvirfqksgkglslwdtqesesgftpilwaeyphwegeiirfeteetrkleisgmpl
gdlfhirfaarspefkkhpavrkepgpglvpvltgrnlkpgwvdyeknhsglwmpkerak
elrdfyatphlvvahtkgtrvvaawderaypwreefhllpkegvrldpsslvqwlnseam
qkhvrtlyrdfvphltlrmlerlpvrreyg

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.