PDB entry 2igo

View 2igo on RCSB PDB site
Description: Crystal structure of pyranose 2-oxidase H167A mutant with 2-fluoro-2-deoxy-D-glucose
Class: oxidoreductase
Keywords: oxidoreductase, gmc oxidoreductase, h167a mutant, 2-fluoro-2-deoxy-d-glucose, rossman fold, phbh fold, homotetramer, 8-alpha-(n3) histidyl flavinylation
Deposited on 2006-09-22, released 2006-10-10
The last revision prior to the SCOP 1.73 freeze date was dated 2006-11-28, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.184
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igoa1, d2igoa2
  • Chain 'B':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igob1, d2igob2
  • Chain 'C':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igoc1, d2igoc2
  • Chain 'D':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igod1, d2igod2
  • Chain 'E':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igoe1, d2igoe2
  • Chain 'F':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igof1, d2igof2
  • Chain 'G':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igog1, d2igog2
  • Chain 'H':
    Compound: Pyranose oxidase
    Species: Trametes ochracea
    Gene: p2o
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZA32
      • engineered (166)
    Domains in SCOP 1.73: d2igoh1, d2igoh2
  • Heterogens: G2F, FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2igoA (A:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoA (A:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2igoB (B:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoB (B:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2igoC (C:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoC (C:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2igoD (D:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoD (D:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2igoE (E:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoE (E:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2igoF (F:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoF (F:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2igoG (G:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoG (G:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2igoH (H:)
mstsssdpffnfakssfrsaaaqkasasslpplpgpdkkvpgmdikydvvivgsgpigct
yarelvgagykvamfdigeidsglkigahkkntveyqknidkfvnviqgqlmsvsvpvnt
lvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvggmstawtcatprfdreqr
pllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlvlnklteeykgqrdfqqip
laatrrsptfvewssantvfdlqnrpntdapeerfnlfpavacervvrnalnseieslhi
hdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnpanppellpslgsyiteqs
lvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastnkhpdwwnekvknhmmqhq
edplpipfedpepqvttlfqpshpwhtqihrdafsygavqqsidsrlivdwrffgrtepk
eenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdmcvmsakiggflpgslpqf
mepglvlhlggthrmgfdekednccvntdsrvfgfknlflggcgniptayganptltams
laiksceyikqnftpspftseaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2igoH (H:)
mdikydvvivgsgpigctyarelvgagykvamfdigeidsglkigahkkntveyqknidk
fvnviqgqlmsvsvpvntlvvdtlsptswqastffvrngsnpeqdplrnlsgqavtrvvg
gmstawtcatprfdreqrpllvkddadaddaewdrlytkaesyfqtgtdqfkesirhnlv
lnklteeykgqrdfqqiplaatrrsptfvewssantvfdlqnrpntdapeerfnlfpava
cervvrnalnseieslhihdlisgdrfeikadvyvltagavhntqllvnsgfgqlgrpnp
anppellpslgsyiteqslvfcqtvmstelidsvksdmtirgtpgeltysvtytpgastn
khpdwwnekvknhmmqhqedplpipfedpepqvttlfqpshpwhtqihrdafsygavqqs
idsrlivdwrffgrtepkeenklwfsdkitdaynmpqptfdfrfpagrtskeaedmmtdm
cvmsakiggflpgslpqfmepglvlhlggthrmgfdekednccvntdsrvfgfknlflgg
cgniptayganptltamslaiksceyikqnftpspft