PDB entry 2ifg

View 2ifg on RCSB PDB site
Description: Structure of the extracellular segment of human TRKA in complex with nerve growth factor
Class: transferase
Keywords: trk, trka, ngf, nerve growth factor, receptor-ligand complex, transferase
Deposited on 2006-09-20, released 2007-02-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: 0.297
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NTRK1, TRK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ifga1, d2ifga2, d2ifga3
  • Chain 'B':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NTRK1, TRK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ifgb1, d2ifgb2, d2ifgb3
  • Chain 'E':
    Compound: Beta-nerve growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: NGFB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ifge1
  • Chain 'F':
    Compound: Beta-nerve growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: NGFB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ifgf1

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ifgA (A:)
cpdaccphgssglrctrdgaldslhhlpgaenltelyienqqhlqhlelrdlrglgelrn
ltivksglrfvapdafhftprlsrlnlsfnaleslswktvqglslqelvlsgnplhcsca
lrwlqrweeeglggvpeqklqchgqgplahmpnascgvptlkvqvpnasvdvgddvllrc
qvegrgleqagwilteleqsatvmksgglpslgltlanvtsdlnrknvtcwaendvgrae
vsvqvnvsfpasvqlhtavemhhwcipfsvdgqpapslrwlfngsvlnetsfifteflep
aanetvrhgclrlnqpthvnngnytllaanpfgqasasimaafmdnp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ifgB (B:)
cpdaccphgssglrctrdgaldslhhlpgaenltelyienqqhlqhlelrdlrglgelrn
ltivksglrfvapdafhftprlsrlnlsfnaleslswktvqglslqelvlsgnplhcsca
lrwlqrweeeglggvpeqklqchgqgplahmpnascgvptlkvqvpnasvdvgddvllrc
qvegrgleqagwilteleqsatvmksgglpslgltlanvtsdlnrknvtcwaendvgrae
vsvqvnvsfpasvqlhtavemhhwcipfsvdgqpapslrwlfngsvlnetsfifteflep
aanetvrhgclrlnqpthvnngnytllaanpfgqasasimaafmdnp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ifgE (E:)
ssshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrd
pnpvdsgcrgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrkavrra

    Sequence, based on observed residues (ATOM records): (download) 
    >2ifgE (E:)
sshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrdg
crgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ifgF (F:)
ssshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrd
pnpvdsgcrgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrkavrra

    Sequence, based on observed residues (ATOM records): (download) 
    >2ifgF (F:)
sshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrdg
crgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrka