PDB entry 2iei

View 2iei on RCSB PDB site
Description: Crystal structure of rabbit muscle glycogen phosphorylase in complex with 3,4-dihydro-2-quinolone
Class: transferase
Keywords: glycogen phosphorylase, diabetes, glucose, transferase
Deposited on 2006-09-19, released 2006-12-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: 0.257
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen phosphorylase, muscle form
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00489
      • conflict (379)
    Domains in SCOPe 2.07: d2ieia_
  • Chain 'B':
    Compound: Glycogen phosphorylase, muscle form
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00489
      • conflict (379)
    Domains in SCOPe 2.07: d2ieib_
  • Heterogens: PLR, FRX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ieiA (A:)
    srplsdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvr
    dhlvgrwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldme
    eleeieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeead
    dwlrygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvnt
    mrlwsakapndfnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvv
    aatlqdiirrfksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerld
    wdkawevtvktcaytnhtvipealerwpvhlletllprhlqiiyeinqrflnrvaaafpg
    dvdrlrrmslveegavkrinmahlciagshavngvarihseilkktifkdfyelephkfq
    nktngitprrwlvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqe
    nklkfaaylereykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvp
    rtvmiggkaapgyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaa
    dlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdr
    ldqrgynaqeyydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeey
    vkcqervsalyknprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpapdek
    ip
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ieiA (A:)
    qisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgrwirtq
    qhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeieedagl
    gngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlrygnpwek
    arpeftlpvhfygrvehtsgakwvdtqvvlampydtpvpgyrnnvvntmrlwsakapyiq
    avldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksfdafpdkvaiq
    lndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvipealerwpvhlletll
    prhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinmahlciagshavngva
    rihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaeiiaerigeeyisdld
    qlrkllsyvddeafirdvakvkqenklkfaaylereyvhinpnslfdvqvkriheykrql
    lnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiiklitaigdvvnhdpvvg
    drlrviflenyrvslaekvipaadlseqistagteasgtgnmkfmlngaltigtmdganv
    emaeeageenffifgmrvedvdrldqrgynaqeyydripelrqiieqlssgffspkqpdl
    fkdivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvirniatsgkfssdrti
    aqyareiwgvepsr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ieiB (B:)
    srplsdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvr
    dhlvgrwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldme
    eleeieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeead
    dwlrygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvnt
    mrlwsakapndfnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvv
    aatlqdiirrfksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerld
    wdkawevtvktcaytnhtvipealerwpvhlletllprhlqiiyeinqrflnrvaaafpg
    dvdrlrrmslveegavkrinmahlciagshavngvarihseilkktifkdfyelephkfq
    nktngitprrwlvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqe
    nklkfaaylereykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvp
    rtvmiggkaapgyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaa
    dlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdr
    ldqrgynaqeyydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeey
    vkcqervsalyknprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpapdek
    ip
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ieiB (B:)
    qisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgrwirtq
    qhykdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeieedaglgn
    gglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlrygnpwekar
    peftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlwsakapgyiq
    avldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksnfdafpdkvai
    qlndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvipealerwpvhlletl
    lprhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinmahlciagshavngv
    arihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaeiiaerigeeyisdl
    dqlrkllsyvddeafirdvakvkqenklkfaaylereykhinpnslfdvqvkriheykrq
    llnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiiklitaigdvvnhdpvv
    gdrlrviflenyrvslaekvipaadlseqistagteasgtgnmkfmlngaltigtmdgan
    vemaeeageenffifgmrvedvdrldnaqeyydripelrqiieqlssgffspkqpdlfkd
    ivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvirniatsgkfssdrtiaqy
    areiwgvepsrqrlpa