PDB entry 2id2

View 2id2 on RCSB PDB site
Description: GAPN T244S mutant X-ray structure at 2.5 A
Class: oxidoreductase
Keywords: aldh, t244, acylation step, hydride transfer, conformation of nicotinamide, oxidoreductase
Deposited on 2006-09-14, released 2007-09-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.176
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • see remark 999 (57)
      • see remark 999 (84)
      • engineered (228)
      • see remark 999 (346)
    Domains in SCOPe 2.07: d2id2a_
  • Chain 'B':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • see remark 999 (57)
      • see remark 999 (84)
      • engineered (228)
      • see remark 999 (346)
    Domains in SCOPe 2.07: d2id2b_
  • Chain 'C':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • see remark 999 (57)
      • see remark 999 (84)
      • engineered (228)
      • see remark 999 (346)
    Domains in SCOPe 2.07: d2id2c_
  • Chain 'D':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Gene: gapN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • see remark 999 (57)
      • see remark 999 (84)
      • engineered (228)
      • see remark 999 (346)
    Domains in SCOPe 2.07: d2id2d_
  • Heterogens: SO4, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2id2A (A:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigk
magmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2id2A (A:)
kqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsyi
eraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmegev
leggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptqg
sisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigkma
gmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelve
kirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicpi
lfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgiae
qlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2id2B (B:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigk
magmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2id2B (B:)
kqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsyi
eraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmegev
leggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptqg
sisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigkma
gmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelve
kirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicpi
lfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgiae
qlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2id2C (C:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigk
magmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2id2C (C:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigkm
agmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2id2D (D:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigk
magmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2id2D (D:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinfsgstgigerigkm
agmrpimlelggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik