PDB entry 2ibg

View 2ibg on RCSB PDB site
Description: Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog
Class: protein binding
Keywords: ihog, hedgehog, fibronectin type III, PROTEIN BINDING
Deposited on 2006-09-11, released 2006-10-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.2
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cg9211-pa
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: iHog, CG9211
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9VM64 (2-213)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ibga1, d2ibga2, d2ibga3
  • Chain 'B':
    Compound: cg9211-pa
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: iHog, CG9211
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9VM64 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ibgb1, d2ibgb2, d2ibgb3
  • Chain 'C':
    Compound: cg9211-pa
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: iHog, CG9211
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9VM64 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ibgc1, d2ibgc2, d2ibgc3
  • Chain 'D':
    Compound: cg9211-pa
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: iHog, CG9211
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9VM64 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d2ibgd1, d2ibgd2, d2ibgd3
  • Chain 'E':
    Compound: Protein hedgehog
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: hh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ibge1
  • Chain 'F':
    Compound: Protein hedgehog
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: hh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ibgf_
  • Chain 'G':
    Compound: Protein hedgehog
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: hh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ibgg_
  • Chain 'H':
    Compound: Protein hedgehog
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: hh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ibgh_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ibgA (A:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrpk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ibgB (B:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgB (B:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2ibgC (C:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgC (C:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2ibgD (D:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgD (D:)
    stypptppnvtrlsdesvmlrwmvprndglpivifkvqyrmvgkrknwqttndnipygkp
    kwnselgksftasvtdlkpqhtyrfrilavysnndnkesntsakfylqpgaaldpmpvpe
    lleieeysetavvlhwslasdadehlitgyyayyrpsssageyfkatiegaharsfkiap
    letatmyefklqsfsaasasefsalkqgrtqrp
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2ibgE (E:)
    lyplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdeegtgadrlm
    skrckeklnvlaysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqsky
    gmlarlaveagfdwvsyvsrrhiycsvksd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgE (E:)
    yplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdrlmskrckekl
    nvlaysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqskygmlarlav
    eagfdwvsyvsrrhiycsvksd
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2ibgF (F:)
    lyplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdeegtgadrlm
    skrckeklnvlaysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqsky
    gmlarlaveagfdwvsyvsrrhiycsvksd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgF (F:)
    lyplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdrlmskrckek
    lnvlaysvmnewpgirllvteseslhyegravtiatsdrdqskygmlarlaveagfdwvs
    yvsrrhiycsvk
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >2ibgG (G:)
    lyplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdeegtgadrlm
    skrckeklnvlaysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqsky
    gmlarlaveagfdwvsyvsrrhiycsvksd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgG (G:)
    lyplvlkqtipnlseytnsasgplegvfkdlvpnynrdilfrrlmskrckeklnvlaysv
    mnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqskygmlarlaveagfdwv
    syvsrrhiycsvks
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2ibgH (H:)
    lyplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrdeegtgadrlm
    skrckeklnvlaysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqsky
    gmlarlaveagfdwvsyvsrrhiycsvksd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ibgH (H:)
    yplvlkqtipnlseytnsasgplegvirrdspkfkdlvpnynrdilfrlmskrckeklnv
    laysvmnewpgirllvteswdedyhhgqeslhyegravtiatsdrdqskygmlarlavea
    gfdwvsyvsrrhiycsvksd