PDB entry 2i9t

View 2i9t on RCSB PDB site
Description: Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter
Class: transcription/DNA
Keywords: protein-DNA complex, transcription/DNA complex
Deposited on 2006-09-06, released 2007-02-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.233
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcription factor p65
    Species: Mus musculus [TaxId:10090]
    Gene: Rela, Nfkb3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q04207 (6-278)
      • cloning artifact (4-5)
    Domains in SCOPe 2.06: d2i9ta1, d2i9ta2, d2i9ta3
  • Chain 'B':
    Compound: Nuclear factor NF-kappa-B p105 subunit
    Species: Mus musculus [TaxId:10090]
    Gene: NFKB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2i9tb1, d2i9tb2
  • Chain 'C':
    Compound: 5'-d(*ap*gp*tp*gp*gp*gp*ap*ap*ap*tp*tp*cp*cp*tp*cp*tp*g)-3'
  • Chain 'D':
    Compound: 5'-d(*cp*ap*gp*ap*gp*gp*ap*ap*tp*tp*tp*cp*cp*cp*ap*cp*t)-3'
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i9tA (A:)
gshmhapyveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtv
rislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisq
riqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapnta
elkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivf
rtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9tA (A:)
hapyveiieqpkqrgmrfrykcegrsagsipgerstdttkthptikingytgpgtvrisl
vtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqt
nnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnrapntaelki
crvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtpp
yadpslqapvrvsmqlrrpsdrelsepmefqylpd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2i9tB (B:)
mgpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivql
vtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmte
acirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaf
lpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkdd
iqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdl
etsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >2i9tB (B:)
gpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivqlv
tngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmtea
cirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftafl
pdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddi
qirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdle
tsepkpflyype

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.