PDB entry 2i7v

View 2i7v on RCSB PDB site
Description: Structure of Human CPSF-73
Class: hydrolase, RNA binding protein
Keywords: polyadenylation, metallo-B-lactamase, pre-mRNA processing, Artemis, V(D)J recombination, double-strand break repair, HYDROLASE, RNA BINDING PROTEIN
Deposited on 2006-08-31, released 2007-01-30
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.224
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cleavage and polyadenylation specificity factor 73 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: CPSF3, CPSF73
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2i7va_
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i7vA (A:)
msaipaeesdqllirplgagqevgrsciilefkgrkimldcgihpglegmdalpyidlid
paeidlllishfhldhcgalpwflqktsfkgrtfmthatkaiyrwllsdyvkvsnisadd
mlytetdleesmdkietinfhevkevagikfwcyhaghvlgaamfmieiagvkllytgdf
srqedrhlmaaeipnikpdiliiestygthihekreerearfcntvhdivnrggrglipv
falgraqelllildeywqnhpelhdipiyyasslakkcmavyqtyvnamndkirkqinin
npfvfkhisnlksmdhfddigpsvvmaspgmmqsglsrelfeswctdkrngviiagycve
gtlakhimsepeeittmsgqklplkmsvdyisfsahtdyqqtsefiralkpphvilvhge
qnemarlkaalireyedndevhievhnprnteavtlnfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2i7vA (A:)
eesdqllirplgagqevgrsciilefkgrkimldcgihpglegmdalpyidlidpaeidl
llishfhldhcgalpwflqktsfkgrtfmthatkaiyrwllsdyvklytetdleesmdki
etinfhevkevagikfwcyhaghvlgaamfmieiagvkllytgdfsrqedrhlmaaeipn
ikpdiliiestygthihekreerearfcntvhdivnrggrglipvfalgraqelllilde
ywqnhpelhdipiyyasslakkcmavyqtyvnannpfvfkhisnlksmdhfddigpsvvm
aspgmmqsglsrelfeswctdkrngviiagycvegtlakhimsepeeittmsgqklplkm
svdyisfsahtdyqqtsefiralkpphvilvhgeqnemarlkaalireyedndevhievh
nprnteavtlnfr