PDB entry 2i66
View 2i66 on RCSB PDB site
Description: Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis
Class: hydrolase
Keywords: the catalytic pocket, reaction product, reaction intermediate, HYDROLASE
Deposited on
2006-08-28, released
2006-09-05
The last revision prior to the SCOPe 2.07 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.185
AEROSPACI score: 0.54
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ADP-ribosyl cyclase 1
Species: Homo sapiens [TaxId:9606]
Gene: CD38
Database cross-references and differences (RAF-indexed):
- Uniprot P28907 (6-End)
- engineered (10)
- engineered (61)
- engineered (125)
- engineered (170)
- engineered (180)
Domains in SCOPe 2.07: d2i66a_ - Chain 'B':
Compound: ADP-ribosyl cyclase 1
Species: Homo sapiens [TaxId:9606]
Gene: CD38
Database cross-references and differences (RAF-indexed):
- Uniprot P28907 (6-End)
- engineered (10)
- engineered (61)
- engineered (125)
- engineered (170)
- engineered (180)
Domains in SCOPe 2.07: d2i66b_ - Heterogens: G1R, G2R, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2i66A (A:)
kreaearwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhp
cditeedyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdlt
wcgefdtskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdk
dstfgsvevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckni
yrpdkflqcvknpedssctsei
Sequence, based on observed residues (ATOM records): (download)
>2i66A (A:)
rwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefd
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssc
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2i66B (B:)
kreaearwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhp
cditeedyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdlt
wcgefdtskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdk
dstfgsvevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckni
yrpdkflqcvknpedssctsei
Sequence, based on observed residues (ATOM records): (download)
>2i66B (B:)
rwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefd
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknpedssc