PDB entry 2i4q

View 2i4q on RCSB PDB site
Description: Human renin/PF02342674 complex
Class: hydrolase
Keywords: renin inhibitor, protein-ligand complex, hydrolase
Deposited on 2006-08-22, released 2006-10-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.23
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: renin
    Species: Homo sapiens [TaxId:9606]
    Gene: REN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00797 (2-335)
      • cloning artifact (0-1)
    Domains in SCOPe 2.06: d2i4qa1, d2i4qa2
  • Chain 'B':
    Compound: renin
    Species: Homo sapiens [TaxId:9606]
    Gene: REN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00797 (2-335)
      • cloning artifact (0-1)
    Domains in SCOPe 2.06: d2i4qb1, d2i4qb2
  • Heterogens: UA4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2i4qA (A:)
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpq
hyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklme
algakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamd
ippptgptwalgatfirkfytefdrrnnrigfalar

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2i4qB (B:)
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpq
hyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklme
algakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamd
ippptgptwalgatfirkfytefdrrnnrigfalar