PDB entry 2i4i

View 2i4i on RCSB PDB site
Description: Crystal Structure of human DEAD-box RNA helicase DDX3X
Class: Hydrolase
Keywords: RNA, HELICASE, DEAD, STRUCTURAL GENOMICS, SGC, Structural Genomics Consortium, Hydrolase
Deposited on 2006-08-22, released 2006-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.189
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent RNA helicase DDX3X
    Species: Homo sapiens [TaxId:9606]
    Gene: DDX3X
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00571 (2-End)
      • cloning artifact (1)
    Domains in SCOPe 2.08: d2i4ia1, d2i4ia2, d2i4ia3
  • Heterogens: AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i4iA (A:)
smveatgnncpphiesfsdvemgeiimgnieltrytrptpvqkhaipiikekrdlmacaq
tgsgktaafllpilsqiysdgpgealramkengrygrrkqypislvlaptrelavqiyee
arkfsyrsrvrpcvvyggadigqqirdlergchllvatpgrlvdmmergkigldfckylv
ldeadrmldmgfepqirriveqdtmppkgvrhtmmfsatfpkeiqmlardfldeyiflav
grvgstsenitqkvvwveesdkrsflldllnatgkdsltlvfvetkkgadsledflyheg
yactsihgdrsqrdreealhqfrsgkspilvatavaargldisnvkhvinfdlpsdieey
vhrigrtgrvgnlglatsffnerninitkdlldllveakqevpswlenmayehhykg

    Sequence, based on observed residues (ATOM records): (download) 
    >2i4iA (A:)
mveatgnncpphiesfsdvemgeiimgnieltrytrptpvqkhaipiikekrdlmacaqt
gsgktaafllpilsqiysdgpgealramkengrygrrkqypislvlaptrelavqiyeea
rkfsyrsrvrpcvvyggadigqqirdlergchllvatpgrlvdmmergkigldfckylvl
deadrmldmgfepqirriveqdtmppkgvrhtmmfsatfpkeiqmlardfldeyiflavg
tsenitqkvvwveesdkrsflldllnatgkdsltlvfvetkkgadsledflyhegyacts
ihgdrsqrdreealhqfrsgkspilvatavaargldisnvkhvinfdlpsdieeyvhrig
rtgrnlglatsffnerninitkdlldllveakqevpswlenmayehhy