PDB entry 2i3z

View 2i3z on RCSB PDB site
Description: rat DPP-IV with xanthine mimetic inhibitor #7
Class: Hydrolase
Keywords: enzyme, peptidase, inhibitor, Hydrolase
Deposited on 2006-08-21, released 2006-12-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.253
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV)
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2i3za1, d2i3za2
  • Chain 'B':
    Compound: Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV)
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2i3zb1, d2i3zb2
  • Heterogens: LIR

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2i3zA (A:)
    rrtytladylkntfrvksyslrwvsdseylykqennillfnaehgnssiflenstfeifg
    dsisdysvspdrlfvlleynyvkqwrhsytasysiydlnkrqliteekipnntqwitwsq
    eghklayvwkndiyvkiephlpshritstgkenvifngindwvyeeeifgaysalwwspn
    gtflayaqfndtgvplieysfysdeslqypktvwipypkagavnptvkffivntdslsst
    tttipmqitapasvttgdhylcdvawvsedrislqwlrriqnysvmaicdydkttlvwnc
    pttqehietsatgwcgrfrpaephftsdgssfykivsdkdgykhicqfqkdrkpeqvctf
    itkgawevisiealtsdylyyisneykempggrnlykiqltdhtnkkclscdlnpercqy
    ysvslskeakyyqlgcrgpglplytlhrstdqkelrvlednsaldkmlqdvqmpskkldf
    ivlnetrfwyqmilpphfdkskkypllidvyagpcsqkadaafrlnwatylasteniiva
    sfdgrgsgyqgdkimhainkrlgtlevedqieaarqflkmgfvdskrvaiwgwsyggyvt
    smvlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfk
    qveyllihgtaddnvhfqqsaqiskalvdagvdfqamwytdedhgiasstahqhiyshms
    hflqqcfslr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2i3zB (B:)
    rrtytladylkntfrvksyslrwvsdseylykqennillfnaehgnssiflenstfeifg
    dsisdysvspdrlfvlleynyvkqwrhsytasysiydlnkrqliteekipnntqwitwsq
    eghklayvwkndiyvkiephlpshritstgkenvifngindwvyeeeifgaysalwwspn
    gtflayaqfndtgvplieysfysdeslqypktvwipypkagavnptvkffivntdslsst
    tttipmqitapasvttgdhylcdvawvsedrislqwlrriqnysvmaicdydkttlvwnc
    pttqehietsatgwcgrfrpaephftsdgssfykivsdkdgykhicqfqkdrkpeqvctf
    itkgawevisiealtsdylyyisneykempggrnlykiqltdhtnkkclscdlnpercqy
    ysvslskeakyyqlgcrgpglplytlhrstdqkelrvlednsaldkmlqdvqmpskkldf
    ivlnetrfwyqmilpphfdkskkypllidvyagpcsqkadaafrlnwatylasteniiva
    sfdgrgsgyqgdkimhainkrlgtlevedqieaarqflkmgfvdskrvaiwgwsyggyvt
    smvlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfk
    qveyllihgtaddnvhfqqsaqiskalvdagvdfqamwytdedhgiasstahqhiyshms
    hflqqcfslr