PDB entry 2i0v

View 2i0v on RCSB PDB site
Description: c-FMS tyrosine kinase in complex with a quinolone inhibitor
Class: transferase
Keywords: Receptor Tyrosine Kinase, Kinase-Inhibitor complex, transferase
Deposited on 2006-08-11, released 2006-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cFMS Tyrosine Kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07333 (Start-143)
      • see remark 999 (144)
      • see remark 999 (161-164)
    • Uniprot P07333 (165-End)
    Domains in SCOPe 2.08: d2i0va_
  • Heterogens: SO4, 6C3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i0vA (A:)
gvdykykqkpkyqvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafg
kvveatafglgkedavlkvavkmlkstahadekealmselkimshlgqhenivnllgact
hggpvlviteyccygdllnflrrkrppgleysynpshnpeeqlssrdllhfssqvaqgma
flaskncihrdvaarnvlltnghvakigdfglardimndsnyivkgnarlpvkwmapesi
fdcvytvqsdvwsygillweifslglnpypgilvnskfyklvkdgyqmaqpafapkniys
imqacwalepthrptfqqicsflqeqaqedrrerd

    Sequence, based on observed residues (ATOM records): (download) 
    >2i0vA (A:)
pkyqvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafg
lgkedavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlvit
eyccygdllnflrrkrqlssrdllhfssqvaqgmaflaskncihrdvaarnvlltnghva
kigdfglardimndsnyivkgarlpvkwmapesifdcvytvqsdvwsygillweifslgl
npypgilvnskfyklvkdgyqmaqpafapkniysimqacwalepthrptfqqicsflqeq
aqe