PDB entry 2hzn

View 2hzn on RCSB PDB site
Description: Abl kinase domain in complex with NVP-AFG210
Class: transferase
Keywords: tyrosine kinase, TRANSFERASE
Deposited on 2006-08-09, released 2007-01-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase ABL1
    Species: Mus musculus [TaxId:10090]
    Gene: ABL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q61258 (6-End)
      • cloning artifact (2-5)
    Domains in SCOPe 2.08: d2hzna2, d2hzna3
  • Heterogens: KIN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hznA (A:)
gamdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvlly
matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
gcpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelgkrgt

    Sequence, based on observed residues (ATOM records): (download) 
    >2hznA (A:)
mdpsspnydkwemertditmkhklgggevyegvwkkysltvavktldtmeveeflkeaav
mkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqiss
ameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtape
slaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvy
elmracwqwnpsdrpsfaeihqafetmfqessi