PDB entry 2hyp

View 2hyp on RCSB PDB site
Description: Crystal structure of Rv0805 D66A mutant
Class: hydrolase
Keywords: metallophosphoesterase, cAMP, phosphodiesterase, bi-nuclear active site, HYDROLASE
Deposited on 2006-08-07, released 2006-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hypothetical protein RV0805
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: icc
    Database cross-references and differences (RAF-indexed):
    • Uniprot O06629
      • engineered (67)
    Domains in SCOPe 2.08: d2hypa1
  • Heterogens: FE, MN, BR, CAC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2hypA (A:)
    gamdrlraaehprpdyvllhisdthliggdrrlygavdaddrlgelleqlnqsglrpdai
    vftgdlaakgepaayrklrglvepfaaqlgaelvwvmgnhddraelrkflldeapsmapl
    drvcmidglriivldtsvpghhhgeirasqlgwlaeelatpapdgtilalhhppipsvld
    mavtvelrdqaalgrvlrgtdvrailaghlhystnatfvgipvsvasatcytqdltvaag
    gtrgrdgaqgcnlvhvypdtvvhsviplgggetvgtfvsp
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hypA (A:)
    prpdyvllhisdthliggddaddrlgelleqlnqsglrpdaivftgdlaakgepaayrkl
    rglvepfaaqlgaelvwvmgnhddraelrkflldeapsmapldrvcmidglriivldtsv
    pghhhgeirasqlgwlaeelatpapdgtilalhhppipsvldmavtvelrdqaalgrvlr
    gtdvrailaghlhystnatfvgipvsvasatcgcnlvhvypdtvvhsvip