PDB entry 2hxf

View 2hxf on RCSB PDB site
Description: KIF1A head-microtubule complex structure in amppnp-form
Class: transport protein
Keywords: microtubule-based motor, TRANSPORT PROTEIN
Deposited on 2006-08-03, released 2006-10-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: EM
Resolution: 10 Å
R-factor: N/A
AEROSPACI score: -0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2hxfa1, d2hxfa2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2hxfb1, d2hxfb2
  • Chain 'C':
    Compound: Kinesin-like protein KIF1A
    Species: Mus musculus [TaxId:10090]
    Gene: Kif1a
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33173 (18-370)
      • engineered (217)
      • linker (371-377)
    Domains in SCOPe 2.05: d2hxfc1
  • Heterogens: MG, GTP, GDP, TA1, ANP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2hxfA (A:)
    mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
    hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
    rirkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
    vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
    slrfdgalnvdltefqtnlvpyprahfplatyapvisaekayheqlsvaeitnacfepan
    qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepp
    tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
    aredmaalekdyeevgvdsvegegeeegeey
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hxfA (A:)
    recisihvgqagvqignacwelyclehgiqpdghvpravfvdleptvidevrtgtyrqlf
    hpeqlitgkedaannyarghytigkeiidlvldrirkladqctglqgfsvfhsfgggtgs
    gftsllmerlsvdygkksklefsiypapqvstavvepynsiltthttlehsdcafmvdne
    aiydicrrnldierptytnlnrligqivssitaslrfdgalnvdltefqtnlvpyprahf
    platyapvisaekayheqlsvaeitnacfepanqmvkcdprhgkymaccllyrgdvvpkd
    vnaaiatiktkrtiqfvdwcptgfkvginyepptvvpggdlakvqravcmlsnttaiaea
    warldhkfdlmyakrafvhwyvgegmeegefsearedmaalekdyeevgvds
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2hxfB (B:)
    mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
    prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
    rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
    epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
    rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
    aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
    lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
    eyqqyqdatadeqgefeeegeedea
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hxfB (B:)
    reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
    railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
    kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
    pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
    fpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmma
    acdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprgl
    kmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvse
    yqqyqd
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2hxfC (C:)
    masmtggqqmgrdpinmpgasvkvavrvrpfnsremsrdskciiqmsgstttivnpkqpk
    etpksfsfdysywshtspedinyasqkqvyrdigeemlqhafegynvcifaygqtgagks
    ytmmgkqekdqqgiipqlcedlfsrindttndnmsysvevsymeiycervrdllnpknkg
    nlrvrehpllgpyvedlsklavtsyndiqdlmdsgnkartvaatnmnetssrshavfnii
    ftqkrhdaetnittekvskislvdlagseradstgakgtrlkeganinkslttlgkvisa
    laemdsgpnknkkkkktdfipyrdsvltwllrenlggnsrtamvaalspadinydetlst
    lryadrakqirntvsvnleltaeewkkkhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hxfC (C:)
    gasvkvavrvrpfnsremsrdskciiqmsgstttivnpkqpketpksfsfdysywshtsp
    edinyasqkqvyrdigeemlqhafegynvcifaygqtgagksytmmgkqekdqqgiipql
    cedlfsrindttndnmsysvevsymeiycervrdllnpknkgnlrvrehpllgpyvedls
    klavtsyndiqdlmdsgnkartvtssrshavfniiftqkrhdaetnittekvskislvdl
    agseaninkslttlgkvisalaemfipyrdsvltwllrenlggnsrtamvaalspadiny
    detlstlryadrakqirntvsvnl