PDB entry 2hwz

View 2hwz on RCSB PDB site
Description: Fab fragment of Humanized anti-viral antibody MEDI-493 (Synagis TM)
Class: immune system
Keywords: Immunoglobulin, Fab fragment, immune system
Deposited on 2006-08-02, released 2007-08-14
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.251
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Immunoglobulin Fab heavy chain
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2HWZ (0-226)
  • Chain 'L':
    Compound: Immunoglobulin Fab light chain
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2HWZ (Start-212)
    Domains in SCOPe 2.02: d2hwzl1, d2hwzl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2hwzL (L:)
diqmtqspstlsasvgdrvtitckcqlsvgymhwyqqkpgkapklliydtsklasgvpsr
fsgsgsgtaftltisslqpddfatyycfqgsgypftfgggtkleikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwzL (L:)
mtqspstlsasvgdrvtitckcqlsvgymhwyqqkpgkapklliydtsklasgvpsrfsg
sgsgtaftltisslqpddfatyycfqgsgypftfgggtkleikrtvaapsvfifppsdeq
lksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlska
dyekhkvyacevthqglsspvtksfnrgec