PDB entry 2hwe

View 2hwe on RCSB PDB site
Description: a comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
Class: Virus
Keywords: RHINOVIRUS COAT PROTEIN, Icosahedral virus, Virus
Deposited on 1994-01-25, released 1994-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-07, with a file datestamp of 2012-03-02.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: human rhinovirus 1a coat protein (subunit vp1)
    Species: Human rhinovirus 1A [TaxId:12134]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwe1_
  • Chain '2':
    Compound: human rhinovirus 1a coat protein (subunit vp2)
    Species: Human rhinovirus 1A [TaxId:12134]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwe.1
  • Chain '3':
    Compound: human rhinovirus 1a coat protein (subunit vp3)
    Species: Human rhinovirus 1A [TaxId:12134]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwe3_
  • Chain '4':
    Compound: human rhinovirus 1a coat protein (subunit vp4)
    Species: Human rhinovirus 1A [TaxId:12134]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hwe.1
  • Heterogens: W54

PDB Chain Sequences:

  • Chain '1':
    Sequence, based on SEQRES records: (download) 
    >2hwe1 (1:)
npvenyidevlnevlvvpnikeshhttsnsaplldaaetghtsnvqpedaietryvitsq
trdemsiesflgrsgcvhisrikvdytdyngqdinftkwkitlqemaqirrkfelftyvr
fdseitlvpciagrgddighivmqymyvppgapipskrndfswqsgtnmsifwqhgqpfp
rfsipflsiasayymfydgydgdntsskygsvvtndmgticsrivtekqklsvvitthiy
hkakhtkawcprppravpythshvtnympetgdvttaivrrntitta

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwe1 (1:)
nyidevlnevlvvpnikeshhttsnsaplldaaetghtsnvqpedaietryvitsqtrde
msiesflgrsgcvhisrikvdytdyngqdinftkwkitlqemaqirrkfelftyvrfdse
itlvpciagrgddighivmqymyvppgapipskrndfswqsgtnmsifwqhgqpfprfsi
pflsiasayymfydgydgdntsskygsvvtndmgticsrivtekqklsvvitthiyhkak
htkawcprppravpythshvtnympetgdvttaivrrntitta

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >2hwe2 (2:)
spsveacgysdrimqitrgdstissddvanavvgygvwphyltpqdatainkptqpdtss
nrfytleskhwngsskgwwwklpdalkdmgifgenmyyhflgrsgytvhvqcnaskfhqg
tllvamipehqlasakhgsvtagyklthpgeagrdvsqerdaslrqpsddswlnfdgtll
gnllifphqfinlrsnnsatlivpyvnavpmdsmlrhnnwclviipisplrsettssniv
pitvsispmcaefsgaraknikq

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwe2 (2:)
drimqitrgdstissddvanavvgygvwphyltpqdatainkptqpdtssnrfytleskh
wngsskgwwwklpdalkdmgifgenmyyhflgrsgytvhvqcnaskfhqgtllvamipeh
qlasakhgsvtagyklthpgeagrdvsqerdaslrqpsddswlnfdgtllgnllifphqf
inlrsnnsatlivpyvnavpmdsmlrhnnwclviipisplrsettssnivpitvsispmc
aefsgaraknikq

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hwe3 (3:)
glpvyitpgsgqfmttddmqspcalpwyhptkeisipgevknliemcqvdtlipvnnvgn
nvgnvsmytvqlgnqtgmaqkvfsikvditstplattligeiasyythwtgslrfsfmfc
gtanttlklllaytppgidepttrkdamlgthvvwdvglqstislvvpwvsashfrltad
nkysmagyitcwyqtnlvvppstpqtadmlcfvsackdfclrmardtdlhiqsgpieq

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >2hwe4 (4:)
gagvsrqnvgthstqnsvsngsslnyfninyfkdaassgasrld

    Sequence, based on observed residues (ATOM records): (download) 
    >2hwe4 (4:)
yfninyfkdaassgasrld