SCOPe 2.05: Structural Classification of Proteins

PDB entry 2hu4

View 2hu4 on RCSB PDB site
Description: N1 neuraminidase in complex with oseltamivir 2
Class: hydrolase
Keywords: N1, neuraminidase, oseltamivir, hydrolase
Deposited on 2006-07-26, released 2006-09-05
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-05-23, with a file datestamp of 2012-05-18.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.237
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4a_
Chain 'B':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4b_
Chain 'C':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4c_
Chain 'D':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4d_
Chain 'E':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4e_
Chain 'F':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4f_
Chain 'G':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4g_
Chain 'H':
Compound: Neuraminidase
Species: Influenza A virus [TaxId:11320]
Gene:
Database cross-references and differences (RAF-indexed):
- Uniprot Q6DPL2 (0-End)
  - engineered mutation (170)
Domains in SCOPe 2.05: d2hu4h_
Heterogens: G39

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2hu4A (A:)
vklagnsslcpingwavyskdnsirigskgdvfvirepfiscshlecrtffltqgallnd
khsngtvkdrsphrtlmscpvgeapspynsrfesvawsasachdgtswltigisgpdnga
vavlkyngiitdtikswrnnilrtqesecacvngscftvmtdgpsngqasykifkmekgk
vvksveldapnyhyeecscypnageitcvcrdnwhgsnrpwvsfnqnleyqigyicsgvf
gdnprpndgtgscgpvssngaygvkgfsfkygngvwigrtkstnsrsgfemiwdpngwte
tdssfsvkqdivaitdwsgysgsfvqhpeltgldcirpcfwvelirgrpkestiwtsgss
isfcgvnsdtvgwswpdgaelpftidk