PDB entry 2hsd

View 2hsd on RCSB PDB site
Description: the refined three-dimensional structure of 3alpha,20beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 1994-03-28, released 1994-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 2.64 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-alpha, 20 beta-hydroxysteroid dehydrogenase
    Species: Streptomyces exfoliatus [TaxId:1905]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19992 (0-252)
      • conflict (107)
    Domains in SCOPe 2.08: d2hsda_
  • Chain 'B':
    Compound: 3-alpha, 20 beta-hydroxysteroid dehydrogenase
    Species: Streptomyces exfoliatus [TaxId:1905]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19992 (0-252)
      • conflict (107)
    Domains in SCOPe 2.08: d2hsdb_
  • Chain 'C':
    Compound: 3-alpha, 20 beta-hydroxysteroid dehydrogenase
    Species: Streptomyces exfoliatus [TaxId:1905]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19992 (0-252)
      • conflict (107)
    Domains in SCOPe 2.08: d2hsdc_
  • Chain 'D':
    Compound: 3-alpha, 20 beta-hydroxysteroid dehydrogenase
    Species: Streptomyces exfoliatus [TaxId:1905]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19992 (0-252)
      • conflict (107)
    Domains in SCOPe 2.08: d2hsdd_
  • Heterogens: NAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hsdA (A:)
ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv
tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt
vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh
pgmtytpmtaetgirqgegnypntpmgrvgepgeiagavvkllsdtssyvtgaelavdgg
wttgptvkyvmgq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hsdB (B:)
ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv
tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt
vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh
pgmtytpmtaetgirqgegnypntpmgrvgepgeiagavvkllsdtssyvtgaelavdgg
wttgptvkyvmgq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hsdC (C:)
ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv
tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt
vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh
pgmtytpmtaetgirqgegnypntpmgrvgepgeiagavvkllsdtssyvtgaelavdgg
wttgptvkyvmgq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hsdD (D:)
ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv
tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt
vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh
pgmtytpmtaetgirqgegnypntpmgrvgepgeiagavvkllsdtssyvtgaelavdgg
wttgptvkyvmgq