PDB entry 2hqu

View 2hqu on RCSB PDB site
Description: Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion
Class: Hydrolase
Keywords: jelly-roll, protein-substrate analogue ligand complex, Hydrolase
Deposited on 2006-07-19, released 2007-07-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-10-19, with a file datestamp of 2016-10-14.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: DUTN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2hqua_
  • Chain 'B':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: DUTN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2hqub_
  • Chain 'C':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: DUTN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2hquc_
  • Heterogens: MG, CL, DUP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2hquA (A:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hquA (A:)
    mqlrfarlsehataptrraagydlysaydytippmekavvktdiqialpsgcygrvaprs
    glaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeieevq
    alddtergsggfgstgkn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2hquB (B:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hquB (B:)
    mqlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrva
    prsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeie
    evqalddtergsggfgstgkn
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2hquC (C:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hquC (C:)
    mqlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrva
    prsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeie
    evqf