PDB entry 2hpp

View 2hpp on RCSB PDB site
Description: Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase-hydrolase inhibitor complex, serine proteinase
Deposited on 1993-04-28, released 1994-01-31
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.157
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: ALPHA-THROMBIN heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2hpp.1
  • Chain 'L':
    Compound: ALPHA-THROMBIN light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2hpp.1
  • Chain 'P':
    Compound: Prothrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00735 (0-78)
      • conflict (74)
    Domains in SCOPe 2.06: d2hppp_
  • Heterogens: 0G7, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2hppH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >2hppH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
kkwiqkvidqf

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2hppL (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >2hppL (L:)
geadcglrplfekksledkterellesyid

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hppP (P:)
cvpdrgreyrgrlavttsgsrclawsseqakalskdqdfnpavplaenfcrnpdgdeega
wcyvadqpgdfeycnlnyc