PDB entry 2hp6

View 2hp6 on RCSB PDB site
Description: Crystal structure of the OXA-10 W154A mutant at pH 7.5
Class: hydrolase
Keywords: class D beta-lactamase, lysine carboxylation, HYDROLASE
Deposited on 2006-07-17, released 2007-07-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.171
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase PSE-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pse2, oxa10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489
      • engineered (135)
    Domains in SCOPe 2.05: d2hp6a_
  • Chain 'B':
    Compound: Beta-lactamase PSE-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pse2, oxa10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489 (1-End)
      • cloning artifact (0)
      • engineered (135)
    Domains in SCOPe 2.05: d2hp6b_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hp6A (A:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfalegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >2hp6A (A:)
sitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiiglet
gviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkkfs
ygnqnisggidkfalegqlrisavnqvefleslylnklsaskenqlivkealvteaapey
lvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkimes
egii

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hp6B (B:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfalegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >2hp6B (B:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfalegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiig