PDB entry 2hnl

View 2hnl on RCSB PDB site
Description: Structure of the prostaglandin D synthase from the parasitic nematode Onchocerca volvulus
Class: transferase
Keywords: Prostaglandin synthase, Glutathione S-transferase, River blindness, Onchocerca volvulus, Immune modulation, TRANSFERASE
Deposited on 2006-07-13, released 2007-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase 1
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hnla1, d2hnla2
  • Chain 'B':
    Compound: Glutathione S-transferase 1
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hnlb1, d2hnlb2
  • Heterogens: GSH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2hnlA (A:)
    assnanqaitsensikpkgklqpqmekytltyfngrgraevirllfalanvsyednritr
    dewkylkprtpfghvpmlnvsgnvlgeshaielllggrfgllgtndweeakimavvlnid
    elfqklipwtheknttkkaelfrnlsesdvmpflgryekflkesttghivgnkvsvadlt
    vfnmlmtlddevkleeypqlasfvnkigqmpgikewikkrpktyf
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hnlA (A:)
    qmekytltyfngrgraevirllfalanvsyednritrdewkylkprtpfghvpmlnvsgn
    vlgeshaielllggrfgllgtndweeakimavvlnidelfqklipwtheknttkkaelfr
    nlsesdvmpflgryekflkesttghivgnkvsvadltvfnmlmtlddevkleeypqlasf
    vnkigqmpgikewikkrpktyf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2hnlB (B:)
    assnanqaitsensikpkgklqpqmekytltyfngrgraevirllfalanvsyednritr
    dewkylkprtpfghvpmlnvsgnvlgeshaielllggrfgllgtndweeakimavvlnid
    elfqklipwtheknttkkaelfrnlsesdvmpflgryekflkesttghivgnkvsvadlt
    vfnmlmtlddevkleeypqlasfvnkigqmpgikewikkrpktyf
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hnlB (B:)
    ekytltyfngrgraevirllfalanvsyednritrdewkylkprtpfghvpmlnvsgnvl
    geshaielllggrfgllgtndweeakimavvlnidelfqklipwtheknttkkaelfrnl
    sesdvmpflgryekflkesttghivgnkvsvadltvfnmlmtlddevkleeypqlasfvn
    kigqmpgikewikkrpktyf