PDB entry 2hmi

View 2hmi on RCSB PDB site
Description: hiv-1 reverse transcriptase/fragment of fab 28/DNA complex
Class: immune system/DNA
Keywords: aids, hiv-1, rt, polymerase
Deposited on 1998-04-10, released 1998-10-14
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.271
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: subunit of v-1 reverse transcriptase
    Species: Human immunodeficiency virus 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (0-557)
      • engineered (279)
    Domains in SCOP 1.73: d2hmia1, d2hmia2
  • Chain 'B':
    Compound: hisubunit of v-1 reverse transcriptase
    Species: Human immunodeficiency virus 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (0-429)
      • engineered (279)
    Domains in SCOP 1.73: d2hmib_
  • Chain 'C':
    Compound: fab fragment of monoclonal antibody 28
    Species: Mus musculus
    Domains in SCOP 1.73: d2hmic1, d2hmic2
  • Chain 'D':
    Compound: fab fragment of monoclonal antibody 28
    Species: Mus musculus
    Domains in SCOP 1.73: d2hmid1, d2hmid2
  • Chain 'E':
    Compound: DNA (5'-d(*ap*tp*gp*gp*cp*gp*cp*cp*cp*gp*ap*ap*cp*ap*gp*gp*gp*ap*c)-3')
  • Chain 'F':
    Compound: DNA (5'-d(*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*gp*cp*gp*cp*cp*a)-3')

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hmiA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hmiB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqle

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hmiC (C:)
diqmtqttsslsaslgdrvtiscsasqdissylnwyqqkpegtvklliyytsslhsgvps
afsgsgsgtdysltisnlepedfatyycqqyskfpwtfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvawaidgsaaangvlnswtdqdskdstysmsstlt
ltadeyeaansytcaathktstspivksfnanec

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hmiD (D:)
qitlkesgpgivqpsqpfrltctfsgfslstsgigvtwirqpsgkglewlatiwwdddnr
ynpslksrltvskdtsnnqaflnmmtvetadtaiyycaqsaitsvtdsamdhwgqgtsvt
vssaattppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavl
qsdlytlsssvtvpsstwpsetvtcnvahpasstkvdkki

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.