PDB entry 2hl5

View 2hl5 on RCSB PDB site
Description: Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued)
Class: structural protein
Keywords: microtubule binding, dynactin, cytoskeleton associated protein, p150Glued, EB1, +TIP protein Complex structure, structural protein
Deposited on 2006-07-06, released 2006-09-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.212
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Microtubule-associated protein RP/EB family member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPRE1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2hl5a_
  • Chain 'B':
    Compound: Microtubule-associated protein RP/EB family member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPRE1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2hl5b_
  • Chain 'C':
    Compound: Dynactin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14203
      • engineered (34)
    Domains in SCOPe 2.06: d2hl5c_
  • Chain 'D':
    Compound: Dynactin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14203
      • engineered (34)
    Domains in SCOPe 2.06: d2hl5d_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hl5A (A:)
gsdeaaelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilya
tdegfvipdeggpqeeqeey

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5A (A:)
aelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilyatd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hl5B (B:)
gsdeaaelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilya
tdegfvipdeggpqeeqeey

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5B (B:)
aelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilyatdeg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2hl5C (C:)
gshmsaeasarplrvgsrvevigkghrgtvayvgmtlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5C (C:)
plrvgsrvevigkghrgtvayvgmtlfatgkwvgvildeakgkndgtvqgrkyftcdegh
gifvrqsqiqvfedga

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2hl5D (D:)
gshmsaeasarplrvgsrvevigkghrgtvayvgmtlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5D (D:)
plrvgsrvevigkghrgtvayvgmtlfatgkwvgvildeakgkndgtvqgrkyftcdegh
gifvrqsqiqvfedga