PDB entry 2hl5

View 2hl5 on RCSB PDB site
Description: Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued)
Class: structural protein
Keywords: microtubule binding, dynactin, cytoskeleton associated protein, p150Glued, EB1, +TIP protein Complex structure, Coiled Coil
Deposited on 2006-07-06, released 2006-09-12
The last revision prior to the SCOP 1.73 freeze date was dated 2006-09-12, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.212
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Microtubule-associated protein RP/EB family member 1
    Species: HOMO SAPIENS
    Gene: MAPRE1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2hl5a1
  • Chain 'B':
    Compound: Microtubule-associated protein RP/EB family member 1
    Species: HOMO SAPIENS
    Gene: MAPRE1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2hl5b1
  • Chain 'C':
    Compound: Dynactin-1
    Species: HOMO SAPIENS
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14203
      • engineered (34)
  • Chain 'D':
    Compound: Dynactin-1
    Species: HOMO SAPIENS
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14203
      • engineered (34)
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hl5A (A:)
gsdeaaelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilya
tdegfvipdeggpqeeqeey

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5A (A:)
aelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilyatd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hl5B (B:)
gsdeaaelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilya
tdegfvipdeggpqeeqeey

    Sequence, based on observed residues (ATOM records): (download) 
    >2hl5B (B:)
aelmqqvnvlkltvedlekerdfyfgklrnielicqenegendpvlqrivdilyatdeg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.