PDB entry 2hk7

View 2hk7 on RCSB PDB site
Description: Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with mercury at 2.5 angstrom resolution
Class: oxidoreductase
Keywords: shikimate pathway, shikimate dehydrogenase, drug design, OXIDOREDUCTASE
Deposited on 2006-07-03, released 2007-06-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.229
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Shikimate dehydrogenase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: aroE
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67049 (0-268)
      • see remark 999 (194)
      • see remark 999 (232)
    Domains in SCOPe 2.08: d2hk7a1, d2hk7a2
  • Chain 'B':
    Compound: Shikimate dehydrogenase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: aroE
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67049 (0-End)
      • see remark 999 (194)
      • see remark 999 (232)
    Domains in SCOPe 2.08: d2hk7b1, d2hk7b2
  • Heterogens: HG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2hk7A (A:)
minaqtqlygvigfpvkhslspvfqnaliryaglnavylafeinpeelkkafegfkalkv
kginvtvpfkeeiiplldyvedtakeigavntvkfengkaygyntdwigflkslkslipe
vkeksilvlgaggasraviyalvkegakvflwnrtkekaiklaqkfplevvnspeevidk
vqvivnttsvglkdedpeifnydlikkdhvvvdiiyketkllkkakekgaklldglpmll
wqgieafkiwngcevpysvaersvrdlrg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hk7B (B:)
minaqtqlygvigfpvkhslspvfqnaliryaglnavylafeinpeelkkafegfkalkv
kginvtvpfkeeiiplldyvedtakeigavntvkfengkaygyntdwigflkslkslipe
vkeksilvlgaggasraviyalvkegakvflwnrtkekaiklaqkfplevvnspeevidk
vqvivnttsvglkdedpeifnydlikkdhvvvdiiyketkllkkakekgaklldglpmll
wqgieafkiwngcevpysvaersvrdlrg

    Sequence, based on observed residues (ATOM records): (download) 
    >2hk7B (B:)
minaqtqlygvigfpvkhslspvfqnaliryaglnavylafeinpeelkkafegfkalkv
kginvtvpfkeeiiplldyvedtakeigavntvkfengkaygyntdwigflkslkslipe
vkeksilvlgaggasraviyalvkegakvflwnrtkekaiklaqkfplevvnspeevidk
vqvivnttsvglkdedpeifnydlikkdhvvvdiiyketkllkkakekgaklldglpmll
wqgieafkiwngcevpysvaersvrdlr