PDB entry 2hij

View 2hij on RCSB PDB site
Description: Crystal Structure of P14 Alanine Variant of Antithrombin
Class: blood clotting/ hydrolase inhibitor
Keywords: thrombin, inhibition, heparin analogue, serine protease 2 inhibitor, blood clotting- hydrolase inhibitor complex
Deposited on 2006-06-29, released 2007-06-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.199
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINC1, AT3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01008
      • engineered (134)
      • engineered (379)
    Domains in SCOPe 2.07: d2hiji1
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2hijl_
  • Heterogens: NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2hijI (I:)
hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
fffaklncrlyrkaakssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
dlyvsdafhkaflevneegaeaaastavviagrslnpnrvtfkanrpflvfirevplnti
ifmgrvanpcvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hijI (I:)
vdictakprdipmnpmciyrspektnrrvwelskansrfattfyqhladskndndnifls
plsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkaakssk
lvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegrit
dvipsaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfry
rrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhm
prfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneega
eaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2hijL (L:)
hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
ifmgrvanpcvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hijL (L:)
vdictakprdipmnpmciyrspatnrrvwelskansrfattfyqhladskndndniflsp
lsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkanksskl
vsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritd
vipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfry
rrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhm
prfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegs
eaaastavviagrslnpnrvtkanrpflvfirevplntiifmgrvanpc