PDB entry 2hij

View 2hij on RCSB PDB site
Description: Crystal Structure of P14 Alanine Variant of Antithrombin
Class: blood clotting/ hydrolase inhibitor
Keywords: thrombin, inhibition, heparin analogue, serine protease 2 inhibitor
Deposited on 2006-06-29, released 2007-06-19
The last revision prior to the SCOP 1.73 freeze date was dated 2007-06-19, with a file datestamp of 2007-06-15.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.199
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: HOMO SAPIENS
    Gene: SERPINC1, AT3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01008
      • engineered (134)
      • engineered (379)
  • Chain 'L':
    Compound: antithrombin-III
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2hijl1
  • Heterogens: NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2hijL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hijL (L:)
    vdictakprdipmnpmciyrspatnrrvwelskansrfattfyqhladskndndniflsp
    lsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkanksskl
    vsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritd
    vipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfry
    rrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhm
    prfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegs
    eaaastavviagrslnpnrvtkanrpflvfirevplntiifmgrvanpc