PDB entry 2hfg

View 2hfg on RCSB PDB site
Description: Crystal structure of hBR3 bound to CB3s-Fab
Class: immune system
Keywords: fab fragment, TNFRSF, antibody-receptor complex, CRD, IMMUNE SYSTEM
Deposited on 2006-06-23, released 2006-11-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: 0.201
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: CB3s Fab heavy chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2hfgh1, d2hfgh2
  • Chain 'L':
    Compound: CB3s Fab light chain (kappa)
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2hfgl1, d2hfgl2
  • Chain 'R':
    Compound: Tumor necrosis factor receptor superfamily member 13C
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFRSF13C, BAFFR, BR3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96RJ3
      • engineered (16)
      • engineered (23)
    Domains in SCOPe 2.05: d2hfgr_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2hfgH (H:)
    evqlvesggglvqpggslrlscaasgftissssihwvrqapgkglewvawvlpsvgftdy
    adsvkgrftisadtskntaylqmnslraedtavyycarrvcynrlgvcaggmdywgqgtl
    vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
    vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hfgH (H:)
    evqlvesggglvqpggslrlscaasgftissssihwvrqapgkglewvawvlpsvgftdy
    adsvkgrftisadtskntaylqmnslraedtavyycarrvcynrlgvcaggmdywgqgtl
    vtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
    lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2hfgL (L:)
    diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
    rfsgsgsgtdftltisslqpedfatyycqqsqispptfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hfgL (L:)
    diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
    rfsgsgsgtdftltisslqpedfatyycqqsqispptfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrge
    

  • Chain 'R':
    Sequence, based on SEQRES records: (download)
    >2hfgR (R:)
    gsyslrgrdapaptpcnpaecfdplvrhcvacgllrtprpkpagasspapr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2hfgR (R:)
    apaptpcnpaecfdplvrhcvacgllr