PDB entry 2heo

View 2heo on RCSB PDB site
Description: General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
Class: Immune System/DNA
Keywords: PROTEIN DLM1-Z-DNA COMPLEX, Immune System-DNA COMPLEX
Deposited on 2006-06-21, released 2006-11-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.248
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Z-DNA binding protein 1
  Species: Mus musculus [TaxId:10090]
  Gene: Zbp1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9QY24 (Start-66)
    • engineered (26)
    • engineered (28)
    • engineered (58)
    • engineered (60-61)
  Domains in SCOPe 2.08: d2heoa_
• Chain 'B':
  Compound: 5'-d(*tp*cp*gp*cp*gp*cp*g)-3'
  
• Chain 'D':
  Compound: Z-DNA binding protein 1
  Species: Mus musculus [TaxId:10090]
  Gene: Zbp1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9QY24
    • engineered (26)
    • engineered (28)
    • engineered (58)
    • engineered (60-61)
  Domains in SCOPe 2.08: d2heod_
• Chain 'E':
  Compound: 5'-d(*tp*cp*gp*cp*gp*cp*g)-3'
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2heoA (A:)
  gshmlstgdnleqkilqvlsddggpvaifqlvkkcqvpkktlnqvlyrlkkedrvsspsp
  kywsigg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2heoA (A:)
  dnleqkilqvlsddggpvaifqlvkkcqvpkktlnqvlyrlkkedrvsspspkywsigg
  

  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >2heoD (D:)
  gshmlstgdnleqkilqvlsddggpvaifqlvkkcqvpkktlnqvlyrlkkedrvsspsp
  kywsigg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2heoD (D:)
  dnleqkilqvlsddggpvaifqlvkkcqvpkktlnqvlyrlkkedrvsspspkywsig
  

  
  
• Chain 'E':
  No sequence available.