PDB entry 2hen

View 2hen on RCSB PDB site
Description: Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
Class: transferase
Keywords: Eph kinase domain, activation, TRANSFERASE
Deposited on 2006-06-21, released 2007-02-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.205
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ephrin type-b receptor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ephb2, Epth3, Nuk, Sek3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54763 (1-End)
      • cloning artifact (0)
      • engineered (133)
    Domains in SCOPe 2.05: d2hena_
  • Chain 'B':
    Compound: ephrin type-b receptor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ephb2, Epth3, Nuk, Sek3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54763 (1-End)
      • cloning artifact (0)
      • engineered (133)
    Domains in SCOPe 2.05: d2henb_
  • Chain 'C':
    Compound: ephrin type-b receptor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ephb2, Epth3, Nuk, Sek3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54763 (1-End)
      • cloning artifact (0)
      • engineered (133)
    Domains in SCOPe 2.05: d2henc_
  • Chain 'D':
    Compound: ephrin type-b receptor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ephb2, Epth3, Nuk, Sek3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54763 (1-End)
      • cloning artifact (0)
      • engineered (133)
    Domains in SCOPe 2.05: d2hend_
  • Heterogens: MG, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2henA (A:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfglsrfleddtsdptytsalggkipirw
    tapeaiqyrkftsasdvwsygivmwevmsygerpywdmtnqdvinaieqdyrlpppmdcp
    salhqlmldcwqkdrnhrpkfgqivntldkmirnpnslkamaplss
    

    Sequence, based on observed residues (ATOM records): (download)
    >2henA (A:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfgpirwtapeaiqyrkftsasdvwsygi
    vmwevmsygerpywdmtnqdvinaieqdyrlpppmdcpsalhqlmldcwqkdrnhrpkfg
    qivntldkmirnpnslkam
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2henB (B:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfglsrfleddtsdptytsalggkipirw
    tapeaiqyrkftsasdvwsygivmwevmsygerpywdmtnqdvinaieqdyrlpppmdcp
    salhqlmldcwqkdrnhrpkfgqivntldkmirnpnslkamaplss
    

    Sequence, based on observed residues (ATOM records): (download)
    >2henB (B:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfgpirwtapeaiqyrkftsasdvwsygi
    vmwevmsygerpywdmtnqdvinaieqdyrlpppmdcpsalhqlmldcwqkdrnhrpkfg
    qivntldkmirnpnslkam
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2henC (C:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfglsrfleddtsdptytsalggkipirw
    tapeaiqyrkftsasdvwsygivmwevmsygerpywdmtnqdvinaieqdyrlpppmdcp
    salhqlmldcwqkdrnhrpkfgqivntldkmirnpnslkamaplss
    

    Sequence, based on observed residues (ATOM records): (download)
    >2henC (C:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfgpirwtapeaiqyrkftsasdvwsygi
    vmwevmsygerpywdmtnqdvinaieqdyrlpppmdcpsalhqlmldcwqkdrnhrpkfg
    qivntldkmirnpnslkam
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2henD (D:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfglsrfleddtsdptytsalggkipirw
    tapeaiqyrkftsasdvwsygivmwevmsygerpywdmtnqdvinaieqdyrlpppmdcp
    salhqlmldcwqkdrnhrpkfgqivntldkmirnpnslkamaplss
    

    Sequence, based on observed residues (ATOM records): (download)
    >2henD (D:)
    skeidiscvkieqvigagefgevcsghlklpgkreifvaiktlksgytekqrrdflseas
    imgqfdhpnvihlegvvtkstpvmiitefmengsldsflrqndgqftviqlvgmlrgiaa
    gmkyladmnyvhralaarnilvnsnlvckvsdfgpirwtapeaiqyrkftsasdvwsygi
    vmwevmsygerpywdmtnqdvinaieqdyrlpppmdcpsalhqlmldcwqkdrnhrpkfg
    qivntldkmirnpnslkam