PDB entry 2hel

View 2hel on RCSB PDB site
Description: Crystal structure of a mutant EphA4 kinase domain (Y742A)
Class: signaling protein, transferase
Keywords: Tyr kinase, activation, SIGNALING PROTEIN, TRANSFERASE
Deposited on 2006-06-21, released 2007-02-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.209
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Eph receptor A4
    Species: Mus musculus [TaxId:10090]
    Gene: Epha4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q80VZ2
      • engineered (151)
    Domains in SCOPe 2.05: d2hela_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2helA (A:)
qgvrtfvdpftfedpnqavrefakeidascikiekvigvgefgevcsgrlkvpgkreicv
aiktlkagytdkqrrdflseasimgqfdhpniihlegvvtkckpvmiiteymengsldaf
lrkndgrftviqlvgmlrgigsgmkylsdmsavhrdlaarnilvnsnlvckvsdfgmsrv
leddpeaayttrggkipirwtapeaiayrkftsasdvwsygivmwevmsygerpywdmsn
qdvikaieegyrlpppmdcpialhqlmldcwqkersdrpkfgqivnmldklirnpnslkr
tgsess

    Sequence, based on observed residues (ATOM records): (download) 
    >2helA (A:)
akeidascikiekvigvgefgevcsgrlkveicvaiktlkytdkqrrdflseasimgqfd
hpniihlegvvtkckpvmiiteymengsldaflrkndgrftviqlvgmlrgigsgmkyls
dmsavhrdlaarnilvnsnlvckvsdfgmsrvkipirwtapeaiayrkftsasdvwsygi
vmwevmsygerpywdmsnqdvikaieegyrlpppmdcpialhqlmldcwqkersdrpkfg
qivnmldklirnpnsl