PDB entry 2hak

View 2hak on RCSB PDB site
Description: Catalytic and ubiqutin-associated domains of MARK1/PAR-1
Class: signaling protein,transferase
Keywords: serine/threonine protein kinase; mark; par-1; kin1; uba domain, signaling protein, transferase
Deposited on 2006-06-13, released 2006-07-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2haka_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakb_
  • Chain 'C':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakc_
  • Chain 'D':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakd_
  • Chain 'E':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hake_
  • Chain 'F':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakf_
  • Chain 'G':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakg_
  • Chain 'H':
    Compound: Serine/threonine-protein kinase MARK1
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2hakh_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hakA (A:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakA (A:)
phignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimkil
nhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqych
qkyivhrdlkaenllldgdmnikiadfgfsneftvgsppyaapelfqgkkydgpevdvws
lgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkkllvlnpikrgsl
eqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmgfardeindalinqkydevm
atyillgrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hakB (B:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakB (B:)
eqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimk
ilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqy
chqkyivhrdlkaenllldgdmnikiadfgfsneftvdvwslgvilytlvsgslpfdglr
ervlrgkyripfymstdcenllkkllvlnprgsleqimkdrwmnvgelkpytepdpdfnd
tkridimvtmgfardeindalinqkydevmatyillgrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2hakC (C:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakC (C:)
eqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimk
ilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqy
chqkyivhrdlkaenllldgdmnikiadfgfsneftvgppyaapelfqgkkydgpevdvw
slgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkkllvlnpikrgs
leqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmgfardeindalinqkydev
matyillgrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2hakD (D:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakD (D:)
qphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqyc
hqkyivhrdlkaenllldgdmnikiadfgfsneftvgppyaapelfqgkkydgpevdvws
lgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkkllvlnpikrgsl
eqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmgfardeindalinqkydevm
atyillgrk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2hakE (E:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakE (E:)
qphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqyc
hqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppyaapelfqgkky
dgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkkllv
lnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmgfardeindal
inqkydevmatyillgrk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2hakF (F:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakF (F:)
qphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqyc
hqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppyaapelfqgkky
dgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkkllv
lnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmgfardeindal
inqkydevmatyillgrk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2hakG (G:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakG (G:)
phignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimkil
nhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqych
qkyivhrdlkaenllldgdmnikiadfgfsneftvsppyaapgpevdvwslgvilytlvs
gslpfdgqnlkelrervlrgkyripfymstdcenllkkllvlnprgsleqimkdrwmnvg
heeeelkpytepdpdfndtkridimvtmgfardeindalinqkydevmatyillgrk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2hakH (H:)
gnsitsatdeqphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakf
rqivsavqychqkyivhrdlkaenllldgdmnikiadfgfsneftvgnkldtfcgsppya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtkridimvtmg
fardeindalinqkydevmatyillgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2hakH (H:)
qphignyrlqktigkgnfakvklarhvltgrevavkiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylvmeyasggevfdylvahgrmkekearakfrqivsavqyc
hqkyivhrdlkaenllldgdmnikiadfgfsneftvgpevdvwslgvilytlvsgslpfd
ripfymstdcenllkkllvlnpikrgsleqimkdrwmnvgheeeelkpytepdpdfndtk
ridimvtmgfardeindalinqkydevmatyillgrk