PDB entry 2h9e

View 2h9e on RCSB PDB site
Description: Crystal Structure of FXa/selectide/NAPC2 ternary complex
Class: hydrolase/hydrolase inhibitor
Keywords: factor Xa, NAPc2, selectide, hydrolase-hydrolase inhibitor complex, blood clotting
Deposited on 2006-06-09, released 2007-02-13
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.222
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: Anti-coagulant protein C2
    Species: Ancylostoma caninum [TaxId:29170]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2h9ec_
  • Chain 'H':
    Compound: coagulation factor x heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2h9eh_
  • Chain 'L':
    Compound: coagulation factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2h9el1
  • Chain 'S':
    Compound: selectide inhibitor DTY-ILE-ARG-LEU-LPD peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2H9E (0-4)
  • Heterogens: PO4, ACT, NA, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2h9eC (C:)
    katmqcgenekydscgskecdkkckydgveeeddeepnvpclvrvchqdcvceegfyrnk
    ddkcvsaedceldnmdfiypgtrn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2h9eC (C:)
    cgenekyddkkckydgvecvceegfyrnkddkcvsaedceldnmdfiypgtr
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2h9eH (H:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2h9eL (L:)
    dgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqn
    svvcscargytladngkaciptgpypcgkqtlerrkrsvaqatsssgeapdsitwkpyda
    adldptenpfdlldfnqtqpergdnnltr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2h9eL (L:)
    csldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqt
    

  • Chain 'S':
    No sequence available.