PDB entry 2h94

View 2h94 on RCSB PDB site
Description: Crystal Structure and Mechanism of human Lysine-Specific Demethylase-1
Class: oxidoreductase
Keywords: Histone Demethylase, OXIDOREDUCTASE
Deposited on 2006-06-08, released 2006-07-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.229
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: AOF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2h94a1, d2h94a2, d2h94a3
  • Heterogens: HG, FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h94A (A:)
sgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltf
eatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsgl
aaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnm
elakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqa
levviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkpp
rditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildw
hfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavr
qvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsav
qrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvagea
agimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgn
dydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqflg
amyt

    Sequence, based on observed residues (ATOM records): (download) 
    >2h94A (A:)
sgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltf
eatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsgl
aaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnm
elakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqa
levviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeastaefl
vkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildwhfanlefa
natplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavrqvrytasg
ceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsavqrmgfgnl
nkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvageaagimenis
ddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgndydlmaqp
itpgiprlffagehtirnypatvhgallsglreagriadqflgamyt