PDB entry 2h7p
View 2h7p on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) complexed with N-(3-chloro-2-methylphenyl)-1-cyclohexyl- 5-oxopyrrolidine-3-carboxamide
Class: oxidoreductase
Keywords: Oxidoreductase, InhA, Enoyl Acyl Carrier Reductase, Pyrrolidine Carboxamide
Deposited on
2006-06-02, released
2006-10-31
The last revision prior to the SCOP 1.73 freeze date was dated
2006-10-31, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.19
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
Species: Mycobacterium tuberculosis
Gene: inhA
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d2h7pa1 - Heterogens: NAD, 468, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2h7pA (A:)
mtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapl
leldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgi
hisaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareag
kygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvak
tvcallsdwlpattgdiiyadggahtqll
Sequence, based on observed residues (ATOM records): (download)
>2h7pA (A:)
tglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapll
eldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgih
isaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagk
ygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvakt
vcallsdwlpattgdiiyadggahtqll