PDB entry 2h6k

View 2h6k on RCSB PDB site
Description: Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Class: gene regulation
Keywords: WD40 WD-repeat histone modification MLL SET chromatin, GENE REGULATION
Deposited on 2006-05-31, released 2006-07-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.149
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: wd-repeat protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6ka_
  • Chain 'B':
    Compound: wd-repeat protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6kb_
  • Chain 'C':
    Compound: Histone H3 K4-Me 9-residue peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2H6K (0-8)
  • Chain 'D':
    Compound: Histone H3 K4-Me 9-residue peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2H6K (0-End)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h6kA (A:)
atqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfekt
isghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsn
livsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtas
gqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekyci
fanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaale
ndktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6kA (A:)
pvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklg
isdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsf
desvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktl
idddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvt
ggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktikl
wksdc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2h6kB (B:)
atqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfekt
isghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsn
livsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtas
gqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekyci
fanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaale
ndktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6kB (B:)
tpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghkl
gisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgs
fdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclkt
lidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsv
tggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktik
lwksdc

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.