PDB entry 2h6j

View 2h6j on RCSB PDB site
Description: Crystal Structure of the Beta F145A Rhodococcus Proteasome
Class: hydrolase
Keywords: 20S proteasome, half proteasome, assembly-dependent activation, HYDROLASE
Deposited on 2006-05-31, released 2006-08-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6ja1
  • Chain 'B':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6jb1
  • Chain 'C':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6jc1
  • Chain 'D':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6jd1
  • Chain 'E':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6je1
  • Chain 'F':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6jf1
  • Chain 'G':
    Compound: proteasome alpha-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcA 1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h6jg1
  • Chain 'H':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jh1
  • Chain 'I':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6ji1
  • Chain 'J':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jj1
  • Chain 'K':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jk1
  • Chain 'L':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jl1
  • Chain 'M':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jm1
  • Chain 'N':
    Compound: proteasome beta-type subunit 1
    Species: Rhodococcus erythropolis [TaxId:1833]
    Gene: prcB 1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53079
      • engineered (209)
    Domains in SCOPe 2.08: d2h6jn1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h6jA (A:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jA (A:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2h6jB (B:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jB (B:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2h6jC (C:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jC (C:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2h6jD (D:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jD (D:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2h6jE (E:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jE (E:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2h6jF (F:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jF (F:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2h6jG (G:)
mtmpyyasaeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrl
gfaavgkynefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyev
eicvaevgrvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaa
vgiavnalrqggagegekrnvdvaslevavldqsrprrafrriagtaleqlvpaepaaas
esapepkpdtetkpadtqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jG (G:)
aeqimrdrselarkgiargrsvvvltfrdgvlfvaenpstalhkvselydrlgfaavgky
nefenlrragivhadmrgysydrrdvtgrslanayaqtlgtifteqpkpyeveicvaevg
rvgspkapqlyritydgsivdeqhfvvmggttepiatamresyradldleaavgiavnal
rqggvdvaslevavldqsrprrafrriagtaleqlvpae

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2h6jH (H:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jH (H:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2h6jI (I:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jI (I:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2h6jJ (J:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jJ (J:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2h6jK (K:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jK (K:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2h6jL (L:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jL (L:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2h6jM (M:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jM (M:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >2h6jN (N:)
mtadrpalrtgdrdtrlsfgsnlssftdylrghapellpenrighrshstrggdgmesgd
laphgttivaltykggvllagdrratqgnliasrdvekvyvtdeysaagiagtagiaiel
vrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqglavvpllvgydldaddes
ragrivsydvvggryeeragyhavgsgslaaksalkkiyspdsdeetalraaieslydaa
dddsatggpdltrgiyptavtitqagavhvseettselarrivaerteqggsar

    Sequence, based on observed residues (ATOM records): (download) 
    >2h6jN (N:)
nlssftdylrghapelldlaphgttivaltykggvllagdrratqgnliasrdvekvyvt
deysaagiagtagiaielvrlfavelehyekiegvpltfdgkanrlasmvrgnlgaamqg
lavvpllvgydldaddesragrivsydvvggryeeragyhavgsgslaaksalkkiyspd
sdeetalraaieslydaadddsatggpdltrgiyptavtitqagavhvseettselarri
va