PDB entry 2h5d

View 2h5d on RCSB PDB site
Description: 0.9A resolution crystal structure of alpha-lytic protease complexed with a transition state analogue, MeOSuc-Ala-Ala-Pro-Val boronic acid
Class: hydrolase/hydrolase inhibitor
Keywords: a-lytic protease, serine protease, acylation transition state, catalysis, protein folding, protein stability, packing distortion, hydrolase-hydrolase inhibitor complex
Deposited on 2006-05-25, released 2006-09-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 0.9 Å
R-factor: 0.081
AEROSPACI score: 1.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-lytic protease
    Species: Lysobacter enzymogenes [TaxId:69]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2h5da_
  • Chain 'B':
    Compound: meosuc-ala-ala-pro-ala boronic acid inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 2H5D (0-4)
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2h5dA (A:)
anivggieysinnaslcsvgfsvtrgatkgfvtaghcgtvnatariggavvgtfaarvfp
gndrawvsltsaqtllprvangssfvtvrgsteaavgaavcrsgrttgyqcgtitaknvt
anyaegavrgltqgnacmgrgdsggswitsagqaqgvmsggnvqsngnncgipasqrssl
ferlqpilsqyglslvtg

  • Chain 'B':
    No sequence available.