PDB entry 2h4f

View 2h4f on RCSB PDB site
Description: Sir2-p53 peptide-NAD+
Class: Hydrolase
Keywords: Sir2 ternary complex, Hydrolase
Deposited on 2006-05-24, released 2006-09-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.194
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent deacetylase
    Species: Thermotoga maritima [TaxId:2336]
    Gene: npdA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2h4fa_
  • Chain 'D':
    Compound: Cellular tumor antigen p53
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NP68
      • modified residue (10)
  • Heterogens: ZN, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h4fA (A:)
mkmkefldllnesrltvtltgagistpsgipdfrgpngiykkysqnvfdidffyshpeef
yrfakegifpmlqakpnlahvllakleekglieavitqnidrlhqragskkvielhgnve
eyycvrcekkytvedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssr
aslmivlgsslvvypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvm
eeggis

    Sequence, based on observed residues (ATOM records): (download) 
    >2h4fA (A:)
mkmkefldllnesrltvtltgagistpsgipdfrgpysqnvfdidffyshpeefyrfake
gifpmlqakpnlahvllakleekglieavitqnidrlhqragskkvielhgnveeyycvr
cekkytvedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssraslmiv
lgsslvvypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvmeeggis

  • Chain 'D':
    No sequence available.