PDB entry 2h46
View 2h46 on RCSB PDB site
Description: Native domain-swapped dimer crystal structure of the Grb2 SH2 domain
Class: hormone/growth factor
Keywords: helix-sheet-helix, HORMONE-GROWTH FACTOR COMPLEX
Deposited on
2006-05-23, released
2006-06-06
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.222
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'E':
Compound: Growth Receptor Binding Protein 2
Species: Homo sapiens [TaxId:9606]
Gene: GRB2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d2h46e_ - Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2h46E (E:)
iemkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlr
dgagkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpqqptyvqhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2h46E (E:)
mkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdg
agkyflwvvkfnslnelvdyhrstsvsrnqqiflrdie