PDB entry 2h2h

View 2h2h on RCSB PDB site
Description: The Structural basis of sirtuin substrate specificity
Class: Hydrolase
Keywords: H4-K79ac, Hydrolase
Deposited on 2006-05-18, released 2006-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-06-27, with a file datestamp of 2012-06-22.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.2
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent deacetylase
    Species: Thermotoga maritima [TaxId:2336]
    Gene: npdA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2h2ha_
  • Chain 'B':
    Compound: histone h4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02309
      • engineered (4)
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h2hA (A:)
mkmkefldllnesrltvtltgagistpsgipdfrgpngiykkysqnvfdidffyshpeef
yrfakegifpmlqakpnlahvllakleekglieavitqnidrlhqragskkvielhgnve
eyycvrcekkytvedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssr
aslmivlgsslvvypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvm
eeggis

    Sequence, based on observed residues (ATOM records): (download) 
    >2h2hA (A:)
mkmkefldllnesrltvtltgagistpsgipdfnvfdidffyshpeefyrfakegifpml
qakpnlahvllakleekglieavitqnidrlhqragskkvielhgnveeyycvrcekkyt
vedvikklessdvplcddcnslirpnivffgenlpqdalreaiglssraslmivlgsslv
vypaaelplitvrsggklvivnlgetpfddiatlkynmdvvefarrvmeeggis

  • Chain 'B':
    No sequence available.