SCOPe 2.06: Structural Classification of Proteins

PDB entry 2h1l

View 2h1l on RCSB PDB site
Description: The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
Class: viral protein
Keywords: p53 Loop-3 conformation change, VIRAL PROTEIN
Deposited on 2006-05-16, released 2006-09-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.16 Å
R-factor: 0.261
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1la_
Chain 'B':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lb_
Chain 'C':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lc_
Chain 'D':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1ld_
Chain 'E':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1le_
Chain 'F':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lf_
Chain 'G':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lg_
Chain 'H':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lh_
Chain 'I':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1li_
Chain 'J':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lj_
Chain 'K':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1lk_
Chain 'L':
Compound: large t antigen
Species: Simian virus 40 [TaxId:10633]
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOPe 2.06: d2h1ll_
Chain 'M':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lm2, d2h1lm3
Chain 'N':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1ln2, d2h1ln3
Chain 'O':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lo2, d2h1lo3
Chain 'P':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lp2, d2h1lp3
Chain 'Q':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lq2, d2h1lq3
Chain 'R':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lr2, d2h1lr3
Chain 'S':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1ls2, d2h1ls3
Chain 'T':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lt2, d2h1lt3
Chain 'U':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lu2, d2h1lu3
Chain 'V':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lv2, d2h1lv3
Chain 'W':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lw2, d2h1lw3
Chain 'X':
Compound: Cellular tumor antigen p53
Species: Homo sapiens [TaxId:9606]
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOPe 2.06: d2h1lx2, d2h1lx3
Heterogens: ZN

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2h1lA (A:)
gseeaeetkqvswklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyh
ekhyanaaifadsknqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfg
stgsadieewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaa
allelcggkalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnl
rdyldgsvkvnlekkhlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhcl
ersefllekriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkf
nvamgigvld