SCOP 1.73: Structural Classification of Proteins

PDB entry 2h1l

View 2h1l on RCSB PDB site
Description: The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
Class: virus/viral protein
Keywords: p53 Loop-3 conformation change
Deposited on 2006-05-16, released 2006-09-12
The last revision prior to the SCOP 1.73 freeze date was dated 2006-09-12, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.16 Å
R-factor: 0.261
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1la1
Chain 'B':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lb1
Chain 'C':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lc1
Chain 'D':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1ld1
Chain 'E':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1le1
Chain 'F':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lf1
Chain 'G':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lg1
Chain 'H':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lh1
Chain 'I':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1li1
Chain 'J':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lj1
Chain 'K':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1lk1
Chain 'L':
Compound: large t antigen
Species: Simian virus 40
Gene: Gene A
Database cross-references and differences (RAF-indexed):
- Uniprot Q9DH70 (Start-369)
Domains in SCOP 1.73: d2h1ll1
Chain 'M':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lm1
Chain 'N':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1ln1
Chain 'O':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lo1
Chain 'P':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lp1
Chain 'Q':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lq1
Chain 'R':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lr1
Chain 'S':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1ls1
Chain 'T':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lt1
Chain 'U':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lu1
Chain 'V':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lv1
Chain 'W':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lw1
Chain 'X':
Compound: Cellular tumor antigen p53
Species: HOMO SAPIENS
Gene: p53
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NP68 (2-End)
  - cloning artifact (1)
Domains in SCOP 1.73: d2h1lx1
Heterogens: ZN

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2h1lA (A:)
gseeaeetkqvswklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyh
ekhyanaaifadsknqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfg
stgsadieewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaa
allelcggkalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnl
rdyldgsvkvnlekkhlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhcl
ersefllekriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkf
nvamgigvld