PDB entry 2h12

View 2h12 on RCSB PDB site
Description: Structure of Acetobacter aceti citrate synthase complexed with oxaloacetate and carboxymethyldethia coenzyme A (CMX)
Class: Transferase
Keywords: acidophile, citrate synthase, acetic acid resistance, allostery, Transferase
Deposited on 2006-05-15, released 2006-09-26
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.195
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12a_
  • Chain 'B':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12b_
  • Chain 'C':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12c_
  • Chain 'D':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12d_
  • Chain 'E':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12e_
  • Chain 'F':
    Compound: citrate synthase
    Species: Acetobacter aceti [TaxId:435]
    Gene: aarA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20901 (Start-435)
      • see remark 999 (84)
      • see remark 999 (105)
    Domains in SCOPe 2.01: d2h12f_
  • Heterogens: OAA, SO4, CMX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2h12A (A:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12A (A:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypanrdlaamrliakiptiaawaykytqgeafiyprnd
lnyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlagstganpfa
ciaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmgfghrvykn
fdprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnvdfysgiil
kamgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdyvplakr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2h12B (B:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12B (B:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptiaawaykytqge
afiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlag
stganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmg
fghrvyknfdprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnv
dfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdy
vplakr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2h12C (C:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12C (C:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptiaawaykytqge
afiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlag
stganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmg
fghrvyknfdprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnv
dfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdy
vplakr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2h12D (D:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12D (D:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypnrdlaamrliakiptiaawaykytqgeafiyprndl
nyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlagstganpfac
iaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmgfghrvyknf
dprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnvdfysgiilk
amgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdyvplakr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2h12E (E:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12E (E:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptiaawaykytqge
afiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlag
stganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmg
fghrvyknfdprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnv
dfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdy
vplakr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2h12F (F:)
msasqkegklstatisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaac
nskitfidgdkgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtl
lheqirnffngfrrdahpmailcgtvgalsafypdandiaipanrdlaamrliakiptia
awaykytqgeafiyprndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqn
aststvrlagstganpfaciaagiaalwgpahgganeavlkmlarigkkenipafiaqvk
dknsgvklmgfghrvyknfdprakimqqtchevltelgikddplldlavelekialsddy
fvqrklypnvdfysgiilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprq
lyigapqrdyvplakr

    Sequence, based on observed residues (ATOM records): (download) 
    >2h12F (F:)
statisvdgksaempvlsgtlgpdvidirklpaqlgvftfdpgygetaacnskitfidgd
kgvllhrgypiaqlaenasyeeviylllngelpnkaqydtftntltnhtllheqirnffn
gfrrdahpmailcgtvgalsafypdpanrdlaamrliakiptiaawaykytqgeafiypr
ndlnyaenflsmmfarmsepykvnpvlaramnrililhadheqnaststvrlagstganp
faciaagiaalwgpahgganeavlkmlarigkkenipafiaqvkdknsgvklmgfghrvy
knfdprakimqqtchevltelgikddplldlavelekialsddyfvqrklypnvdfysgi
ilkamgiptsmftvlfavarttgwvsqwkemieepgqrisrprqlyigapqrdyvplakr