PDB entry 2gww

View 2gww on RCSB PDB site
Description: Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
Class: cell adhesion, structural protein
Keywords: protein complex, CELL ADHESION, STRUCTURAL PROTEIN
Deposited on 2006-05-07, released 2006-11-14
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: 0.232
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18206 (8-265)
      • expression tag (7)
    Domains in SCOPe 2.03: d2gwwa1, d2gwwa2
  • Chain 'B':
    Compound: IpaA
    Species: Shigella flexneri [TaxId:623]
    Database cross-references and differences (RAF-indexed):
    • GB AAP78988 (Start-29)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gwwA (A:)
mehhhhhhmpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavs
nlvrvgketvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgs
rgilsgtsdllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkma
kmiderqqelthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnf
tvekmsaeineiirvlqltswdedaw

    Sequence, based on observed residues (ATOM records): (download) 
    >2gwwA (A:)
hmpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgk
etvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgt
sdllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderq
qelthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsa
eineiirvlqltswdedaw

  • Chain 'B':
    No sequence available.