PDB entry 2gv2

View 2gv2 on RCSB PDB site
Description: MDM2 in complex with an 8-mer p53 peptide analogue
Class: Ligase
Keywords: Optimized protein-protein interaction. Synthetic peptide. Alpha helix binding protein
Deposited on 2006-05-02, released 2006-09-05
The last revision prior to the SCOP 1.73 freeze date was dated 2006-09-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.192
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquitin-protein ligase e3 mdm2
    Species: HOMO SAPIENS
    Gene: MDM2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gv2a1
  • Chain 'B':
    Compound: 8-mer p53 peptide analogue
    Species: synthetic, synthetic
  • Heterogens: ACE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gv2A (A:)
gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvnqqessdsgtsvsen

    Sequence, based on observed residues (ATOM records): (download) 
    >2gv2A (A:)
etlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycsndllgd
lfgvpsfsvkehrkiytmiyrnlvvvnq

  • Chain 'B':
    No sequence available.